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Featured Articles
January 5, 2026 by Margarida Maia, PhD

Top 5 PNH stories of 2025

In 2025, PNH News delivered timely coverage of the latest research developments and advances in care related to paroxysmal nocturnal hemoglobinuria (PNH). To close the year, we’ve compiled the five most-read stories. As we move into 2026, we remain committed to supporting the PNH community with clear reporting…

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An illustration shows a close-up view of red and white blood cells.
December 22, 2025 by Steve Bryson PhD

Rare case of PNH plus lymphoma highlights management challenges

A rare case of paroxysmal nocturnal hemoglobinuria (PNH) coexisting with diffuse large B-cell lymphoma (DLBCL), a type of blood cancer, was chronicled in a new report that sought to elucidate some of the challenges that can come with the management of the acquired blood disorder co-occurring with this cancer.

An illustration provides a close-up view of red blood cells.
December 15, 2025 by Steve Bryson PhD

PiaSky treatment for PNH means fewer blood transfusions: Analysis

Treatment with PiaSky (crovalimab-akkz) controls hemolysis — the destruction of red blood cells in the body — in nearly all people with paroxysmal nocturnal hemoglobinuria (PNH), according to the results of a pooled analysis of published clinical trials. Further, the data also showed that about two-thirds of individuals…

A pregnant woman is shown walking while holding her abdomen.
December 8, 2025 by Marisa Wexler MS

Empaveli safely manages hard-to-control PNH during pregnancy

Empaveli (pegcetacoplan) was safely administered during a woman’s pregnancy to manage hard-to-control paroxysmal nocturnal hemoglobinuria (PNH), according to a recent study. Results showed that Empaveli effectively controlled the mother’s PNH, and the baby was born without complications. There were no detectable signs of the medication in…

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Featured ColumnFinding the strength to rise again after a scary night in the ER

There may be moments in life with PNH when fear takes the wheel, but there’s also strength in rising again, says columnist Shaquilla Gordon.

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Click the link below to find all the latest news related to PNH.

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Sponsored Post
Sponsored Content by Alexion

Living Fully With PNH: One Patient’s Journey

Perspectives

  1. Main banner for Shaquilla Gordon's column
    December 2, 2025 by Shaquilla Gordon

    Finding the strength to rise again after a scary night in the ER

  2. Main banner for Shaquilla Gordon's column
    November 25, 2025 by Shaquilla Gordon

    I give thanks to my PNH support system, my family, my fortress

  3. Main banner for Shaquilla Gordon's column
    November 11, 2025 by Shaquilla Gordon

    Family planning can be more complicated with a PNH diagnosis

  4. Main banner for Shaquilla Gordon's column
    November 4, 2025 by Shaquilla Gordon

    Living with the fear of aplastic anemia while managing PNH

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    October 21, 2025 by Shaquilla Gordon

    Facing the ‘what-ifs’ of PNH complications

  6. Main banner for Shaquilla Gordon's column
    October 7, 2025 by Shaquilla Gordon

    Finding the right doctor to partner with in my PNH care

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